15-Night Cruise on Serenade Of The SeasPanama Canal Eastward Cruise - Weather

The Serenade Of The Seas sails a 15-night Panama Canal Eastward Cruise itinerary with Royal Caribbean Cruises, departing San Diego, California on October 7, 2027. It's a classic Mexican Riviera cruise. Travelers sailing in October can generally expect warm, dry, and reliably sunny Pacific-coast weather. Ports of call include San Diego, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, with 5 more along the way. Use the day-by-day forecast below to plan what to pack for each stop.

1. Day 1 — Thursday, Oct 7, 2027 — San Diego, California

   San Diego, California is a scheduled port of call on day 1 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 72°F.

2. Day 2 — Sunday, Oct 10, 2027 — Puerto Vallarta, Mexico

   Puerto Vallarta, Mexico is a scheduled port of call on day 2 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 81°F.

3. Day 3 — Wednesday, Oct 13, 2027 — Puerto Quetzal, Guatemala

   Puerto Quetzal, Guatemala is a scheduled port of call on day 3 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 83°F.

4. Day 4 — Friday, Oct 15, 2027 — Puntarenas, Costa Rica

   Puntarenas, Costa Rica is a scheduled port of call on day 4 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: rain, overcast with highs near 81°F.

5. Day 5 — Sunday, Oct 17, 2027 — Panama Canal

   Panama Canal is a scheduled port of call on day 5 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 83°F.

6. Day 6 — Monday, Oct 18, 2027 — Cartagena, Colombia

   Cartagena, Colombia is a scheduled port of call on day 6 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 88°F.

7. Day 7 — Wednesday, Oct 20, 2027 — George Town, Grand Cayman

   George Town, Grand Cayman is a scheduled port of call on day 7 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 83°F.

8. Day 8 — Friday, Oct 22, 2027 — Tampa, Florida

   Tampa, Florida is a scheduled port of call on day 8 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 84°F.