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Loading Travel Forecast…Loading Travel Forecast…Loading Travel Forecast…The Serenade Of The Seas sails a 15-night Panama Canal Eastward Cruise itinerary with Royal Caribbean Cruises, departing San Diego, California on October 7, 2027. It's a classic Mexican Riviera cruise. Travelers sailing in October can generally expect warm, dry, and reliably sunny Pacific-coast weather. Ports of call include San Diego, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, with 5 more along the way. Use the day-by-day forecast below to plan what to pack for each stop.
San Diego, California is a scheduled port of call on day 1 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 72°F.
Day 2 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
Day 3 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
Puerto Vallarta, Mexico is a scheduled port of call on day 4 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 81°F.
Day 5 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
Day 6 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
Puerto Quetzal, Guatemala is a scheduled port of call on day 7 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 83°F.
Day 8 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
Puntarenas, Costa Rica is a scheduled port of call on day 9 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: overcast with highs near 81°F.
Day 10 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
Panama Canal is a scheduled port of call on day 11 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 83°F.
Cartagena, Colombia is a scheduled port of call on day 12 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 88°F.
Day 13 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
George Town, Grand Cayman is a scheduled port of call on day 14 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas. Expected weather: partially cloudy with highs near 83°F.
Day 15 of 16 is a day at sea aboard Serenade Of The Seas, cruising between ports on the Panama Canal Eastward Cruise itinerary.
Tampa, Florida is a scheduled port of call on day 16 of the 15-night Panama Canal Eastward Cruise cruise on Serenade Of The Seas.
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